Socio-economic factors such as barriers to health and childhood services, inadequate sanitation and poor water supply suggested an unfavourable impact on the transmission of dengue, Zika and chikungunya in all three ecosystems. The transmission of Zika during the 2016 epidemic appeared to decrease circulation of dengue in Cúcuta, an area of sustained high incidence of dengue. Average temperature, minimum temperature and wind speed were strongly correlated with disease incidence. Correlational analyses were conducted with both generalised linear models and generalised additive models for the geographical data. These locations were confirmed as three different ecosystems given their contrasted geographic, climatic and socio-economic profiles. Here we present an integrated analysis of the reported arbovirus cases between 20 and local climate and socio-economic profiles of three distinct Colombian municipalities (Bello, Cúcuta and Moniquirá). The arrival of the Zika and chikungunya viruses to South America increased the complexity of transmission and morbidity caused by these viruses co-circulating in the same vector mosquito species. Dengue, Zika and chikungunya are diseases of global health significance caused by arboviruses and transmitted by the mosquito Aedes aegypti, which is of worldwide circulation.
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